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RECORD NUMBER: 28 OF 96

Main Title Effects of Selected Water Toxicants on the in vitro Activity of Fish Carbonic Anhydrase.
Author Christensen, G. M. ; Tucker., J. H. ;
CORP Author Environmental Research Lab.-Duluth, Minn.
Year Published 1975
Report Number EPA/600/J-76/010;
Stock Number PB-265 284
Additional Subjects Toxicity ; Catfishes ; Fishes ; Carbonic anhydrase inhibitors ; Metals ; Toxicology ; Physiochemical properties ; Water quality ; Dosage ; Water pollution ; In vitro analysis ; Enzyme inhibitors ; Pesticides ; Cations ; Anions ; Experimental data ; Blood ; Erythrocytes ; Physiochemical properties ; Reprints ; Ictalurus punctatus ; Water pollution effects(Animals) ; Chemicals ; Toxic substances
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NTIS  PB-265 284 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 14p
Abstract Carbonic anhydrase (CA, carbonate hydro-lyase EC 4.2.1.1) from lysed red blood cells of the channel catfish (Ictalurus punctatus) was studied to determine physico-chemical kinetic properties and relative sensitivity to 56 chemicals of significance in water quality research. In general, enzyme activity was strongly reduced by heavy metal inorganic cations; less strongly by organometallic cations, some anions, and certain pesticides; and weakly inhibited by light metal cations and organometallic and organic compounds. Dose-response curves were qualitatively similar in most cases.
Supplementary Notes Revision of report dated 5 Jun 75.
Availability Notes Pub. in Chem-Biol. Interactions, v13 p181-192 1976.
NTIS Title Notes Journal article.
Title Annotations +++Reprint: Effects of Selected Water Toxicants on the in vitro Activity of Fish Carbonic Anhydrase.
PUB Date Free Form 3 Nov 75
Category Codes 6A; 6T; 6F; 13B; 57B; 57Y; 57H; 68D; 98F
NTIS Prices Not available NTIS
Primary Description 600/03
Document Type NT
Cataloging Source NTIS/MT
Control Number 323714389
Origin NTIS
Type CAT