| Main Title |
Review of Di(2-Ethylhexyl)Phthalate (DEHP) Risk Assessments. |
| Author |
Beliles, R. ;
Salinas, J. ;
Kluwe, W. ;
|
| CORP Author |
Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment. ;California Dept. of Health Services, Sacramento. ;Battelle Columbus Labs., OH. |
| Publisher |
cFeb 89 |
| Year Published |
1989 |
| Report Number |
EPA/600/J-92/237 ;OHEA-C-467; |
| Stock Number |
PB92-198613 |
| Additional Subjects |
Diethylhexyl phthalates ;
Toxicity ;
Environmental pollutants ;
Risk assessment ;
Liver neoplasms ;
Rats ;
Mice ;
Health hazards ;
Humans ;
Adenoma ;
Carcinoma ;
Reprints ;
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB92-198613 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
12p |
| Abstract |
Di(2-ethylhexyl)phthalate (DEHP) is the prototype compound of a class of compounds known collectively as the phthalate esters. Lifetime bioassays in rats and mice have indicated that DEHP produces liver tumors in these species when incorporated into the diet. The result has led governmental agencies and representatives of the private sector to attempt to estimate potential human cancer risks from exposure to DEHP and related phthalates in the environment. At least five such assessments have been conducted, each of which comes to a different conclusion regarding the magnitude of human cancer risks. In April 1988, the U.S. Environmental Protection Agency convened a workshop on DEHP risk assessment to compare five assessments of DEHP, to identify the reasons for the differences among them, and to discuss the use of pharmacokinetics and mechanistic information in the assessment of human health risk. |
| Supplementary Notes |
Presented at the EPA Workshop on DEHP Risk Assessment, Bethesda, Maryland, April 19-20, 1988. Pub. in Drug Metabolism Reviews, v21 n1 p3-12 1989. Prepared in cooperation with California Dept. of Health Services, Sacramento, and Battelle Columbus Labs., OH. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Review of Di(2-Ethylhexyl)Phthalate (DEHP) Risk Assessments. |
| Category Codes |
57Y; 68G |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/21 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
224126808 |
| Origin |
NTIS |
| Type |
CAT |
