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RECORD NUMBER: 36 OF 335

Main Title Combining Pharmacokinetic and Cancer Bioassay Data.
Author Whittemore., A. S. ;
CORP Author Stanford Univ., CA. Dept. of Family, Community and Preventive Medicine.;National Institutes of Health, Bethesda, MD.;Electric Power Research Inst., Palo Alto, CA.;Alfred P. Sloan Foundation, New York.;Health Effects Research Lab., Research Triangle Park, NC.
Publisher 1986
Year Published 1986
Report Number NIH-PHS-00070 ;NIH-PHS-CA-23214; EPA/600/D-90/047;
Stock Number PB90-246125
Additional Subjects Toxicology ; Carcinogens ; Bioassay ; Exposure ; Humans ; Laboratory animals ; Metabolism ; Reprints ; Pharmacokinetics ; Risk assessment ; Carcinogenicity tests ; Predictive value of tests ; Dose-response relationships ; Species diversity
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NTIS  PB90-246125 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 16p
Abstract Despite formidable sources of uncertainty, risk assessments are needed to avoid the extremes of either banning or allowing all exposures to potentially harmful chemicals. The paper addresses methods for reducing uncertainty in relationships between human exposures and disease, particularly cancer. Attention will focus on possible improvements in the use of animal experiments to predict human cancer risks.
Supplementary Notes Proceedings of New Directions on the Extrapolation of Health Risks from Animals to Man, v2: Toxicokinetics, San Diego, CA., March 1986. Sponsored by National Institutes of Health, Bethesda, MD., Electric Power Research Inst., Palo Alto, CA., Alfred P. Sloan Foundation, New York, and Health Effects Research Lab., Research Triangle Park, NC.
Title Annotations Reprint: Combining Pharmacokinetic and Cancer Bioassay Data.
Category Codes 57Y
NTIS Prices PC A03/MF A01
Primary Description 600/10
Document Type NT
Cataloging Source NTIS/MT
Control Number 024228667
Origin NTIS
Type CAT