||PNAS in a Series of Aromatic Process and Extender Oils are Cancer Suspect Agents with Attachments of an Interim Report and Sample Letters to Customers.
||Shell Oil Co., Houston, TX.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Carcinogenic effects ;
Animal experimentation ;
Laboratory experimentation ;
DUTREX oils ;
Polynuclear aromatics(PNA) ;
Dermal route ;
Polycyclic aromatic hydrocarbons ;
Cancer suspect agents
||Some EPA libraries have a fiche copy filed under the call number shown.
||Shell Oil Company is a basic producer of a series of eromatic process and extender oils which we market under our DUTREX(R) trademark. The oils contain polynuclear aromatics (PNA) or polycyclic aromatic hydrocarbons (PCAH). Since we became aware of the published skin cancer results of animal studies with known PNA materials, we have warned our customers that DUTREX oils do contain PNA's and are, therefore, cancer suspect agents. Attached is the interim report of a study conducted in mice with DUTREX oils. The study was started in 1976 at the Tunstall (England) Laboratories of Shell International Chemical Company. Exposure is via the dermal route. The findings confirm our concern that this product, containing PNA's at significantly high levels, can elicit a positive carcinogenic response in test animals.
||The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
||Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at email@example.com. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA.
||PC A04/MF A01