Main Title |
Effect of 2 percent venous carboxyhemoglobin on exercise-induced angina pectoris / |
Author |
Aronow, Wilbert S.
|
CORP Author |
Veterans Administration Medical Center, Long Beach, CA.;Health Effects Research Lab., Research Triangle Park, NC. |
Publisher |
U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory, |
Year Published |
1981 |
Report Number |
EPA/600/1-81/012 |
Stock Number |
PB81-152480 |
Subjects |
Angina Pectoris ;
Carbon Monoxide--adverse effects ;
Hemoglobins--analysis
|
Additional Subjects |
Angina pectoris ;
Carbon monoxide ;
Toxicology ;
Concentration(Composition) ;
Exposure ;
Coronary artery disease ;
Patients ;
Exercise(Physiology) ;
Epidemiology ;
Risk ;
Air quality ;
Carboxyhemoglobin ;
Angina pectoris ;
Toxic substances ;
Environmental health ;
Air pollution effects(Humans)
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB81-152480 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
49 pages ; 28 cm |
Abstract |
In a double-blind, randomized, crossover study, 14 patients with angina pectoris who breathed carbon monoxide 50 ppm for 1 hour to raise the mean venous carboxyhemoglobin from 1.09 to 2.02% had a reduction in mean exercise time until angina pectoris from 321.7 to 289.2 seconds, P<0.001. After breathing compressed, purified air to reduce the mean venous carboxyhemoglobin from 1.07 to 1.00% , there was an insignificant increase in mean exercise time until angina pectoris from 324.5 to 330.3 seconds. In comparison with the control period or after breathing compressed purified air, a 2.02% venous carboxyhemoglobin level caused a reduction in exercise time until angina pectoris, P<0.001, no significant change in resting sytolic blood pressure times heart rate, a reduction in systol blood pressure times heart rate at angina pectoris, P<0.001, and no significant change in exercise-induced ischemis S-T segment depression. These data indicate that a 2% venous carboxyhemoglobin level aggravates angina pectoris. |
Notes |
"January 1981." "EPA 600/1-81-012." Final report. Sponsored by the Health Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency. Includes bibliographical references (leaves 31-33). Microfiche. |
Place Published |
Research Triangle Park, NC : |
Corporate Au Added Ent |
Health Effects Research Laboratory (Research Triangle Park, N.C.) ; Veterans Administration Medical Center (Long Beach, CA). |
PUB Date Free Form |
1981. |
NTIS Prices |
PC A03/MF A01 |
BIB Level |
m |
Cataloging Source |
OCLC/T |
OCLC Time Stamp |
20020123122650 |
Language |
eng |
Origin |
NTIS |
Type |
MERGE |
OCLC Rec Leader |
01415nam 2200325Ka 45020 |