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RECORD NUMBER: 6 OF 14

Main Title Five-day Repeated Dose Inhalation Toxicity Study in Rats of Cumene with Cover Letter.
CORP Author Gulf Oil Exploration and Production Co., Oklahoma City, OK.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1985
Report Number 878216016
Stock Number OTS0206783
Additional Subjects Toxicology ; Health effects ; Cumene (98-82-8) ; Subchronic Toxicity ; Mammals ; Rats ; Inhalation ; Toxic substances ; Laboratory animals ; CAS No 98-82-8
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NTIS  OTS0206783 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 29p
Abstract Cumene (CAS No. 98-82-8) was evaluated for subchronic toxicity. The test substance was administered by inhalation to rats (5/sex/group) 6 hours/day for 5 days at concentrations of 0, 2,000, or 5,000 ppm. All rats in the highest exposure group died after 2 days; necropsy revealed congestion of tissues, red fluid filled bladders, and excessive ocular and nasal accumulations. The females of the 2,000 ppm group had hypothermia and a significant weight loss, and all animals in this group had labored respiration and ocular and nasal discharge.
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PUB Date Free Form 1985
Category Codes 57Y; 57U; 68G; 99; 44G
NTIS Prices PC A03/MF A03
Document Type NT
Cataloging Source NTIS/MT
Control Number 028801080
Origin NTIS
Type CAT