| Main Title |
Initial Submission: Acute Toxicity of Phosphorochloridic Acid, Dithyl Ester in Rats, Mice, and Guinea Pigs with Cover Letter dated 08/24/1992. |
| CORP Author |
Eastman Kodak Co., Rochester, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1992 |
| Report Number |
8EHQ-0992-10578 |
| Stock Number |
OTS0570912 |
| Additional Subjects |
Toxicology ;
Health effects ;
Toxic substances ;
Phosphorochloridic acid ;
Diethyl ester ;
Acute toxicity ;
Mammals ;
Rats ;
Oral ;
Gavage ;
Parenteral ;
Intraperitoneal ;
Mice ;
Guinea pigs ;
Dermal ;
CAS No 814-49-3
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0570912 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
5p |
| Abstract |
The report pertains to phosphorochloridic acid, diethyl ester (synonym: diethylphosphorochloridate) (CAS No. 814-49-3) and is being submitted because of lethality observed in an acute oral toxicity test in mice and severe skin irritation observed in an acute dermal irritation study in guinea pigs. The oral LD, is 100 mg/kg in mice. Mice dosed at 50 mg/kg showed a 65% reduction in cholinesterase. The dermal LD90 in guinea pigs is 0.05-0.1 cc/kg. The report is being identified as a study involving other than human effects (Unit II.B.2.b of CAP Agreement). |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
2 Sep 1992 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A01/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
018800310 |
| Origin |
NTIS |
| Type |
CAT |
