| Main Title |
Initial Submission: Acute Oral Toxicity and Skin Absorption and Irritation of 3-Chloropropionitrile in Rats and Guinea Pigs with Cover Letter dated 08/26/1992. |
| CORP Author |
Eastman Kodak Co., Rochester, NY.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1992 |
| Report Number |
EPA-OTS-88-920009469 |
| Stock Number |
OTS0571125 |
| Additional Subjects |
Toxicology ;
Health effects ;
3-Chloroproprionitrile ;
Acute toxicity ;
Mammals ;
Rats ;
Oral ;
Gavage ;
Primary dermal irritation ;
Guinea pigs ;
Dermal ;
CAS No 542-76-7
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0571125 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
5p |
| Abstract |
The report pertains to 3-chloropropanenitrile (synonym: 3-chloropropionitrile) (CAS No. 542-76-7) and is being submitted because of lethality with central nervous system (CNS) signs observed in an acute oral toxicity study in rats. The oral LD50 is 10-50 mg/kg in rats. The material is also a slight skin irritant. The dermal LD50 is 0.05-0.1 cc/kg in guinea pigs. The report is being identified as a study involving other than human effects (Unit II.B.2.b of CAP Agreement). |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
26 Aug 1992 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A01/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
018801560 |
| Origin |
NTIS |
| Type |
CAT |
