Full Record Display for the EPA National Library Catalog
RECORD NUMBER: 1 OF 2| Main Title | Evaluation of Chloroethane Vg and Its Components in the Ames Salmonella/Mammalian Microsome Mutagenicity Assay with Attachments. | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CORP Author | Dow Chemical Co., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. | |||||||||||
| Year Published | 2000 | |||||||||||
| Report Number | 86-890001189 | |||||||||||
| Stock Number | OTS0520701 | |||||||||||
| Additional Subjects | Toxicology ; Health effects ; Chloroethane (75-52-5) ; Genotoxicity ; Gene Mutations ; Bacteria ; In Vitro ; Toxic substances ; Laboratory animals ; CAS No 71-55-6 ; CAS No 75-52-5 ; CAS No 79-24-3 ; CAS No 115-19-5 ; CAS No 26249-20-7 | |||||||||||
| Holdings |
|
|||||||||||
| Collation | 30p | |||||||||||
| Abstract | The mutagenicity of Chlorothene VG solvent and its components (1,1,1-trichloroethane (93.33%), 2,-methyl-3-butyn-2-ol, nitromethane, nitroethane, t-amyl alcohol, and 1,2-butylene oxide) was evaluated in Salmonella tester strains TA98, TA100, TA1535, TA1537, and TA1538, both in the presence and absence of added metabolic activation by Aroclor-induced rat liver S9 fraction. Based on the results of preliminary bacterial toxicity testing, Chlorothene VG was tested at concentrations of 20,664, 41,328, or 165,310 ppm using the dessicator method. Chlorothene VG caused a reproducible positive response in tester strain TA1535, both in the presence and absence of S9 activation. The material did not cause a reproducible positive response in strains TA98, TA1537, or TA1538, either in the presence or absence of activation, although TA100 exhibited a trend toward a positive response. | |||||||||||
| Supplementary Notes | The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. | |||||||||||
| Availability Notes | Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. | |||||||||||
| PUB Date Free Form | 2000 | |||||||||||
| Category Codes | 57Y; 57U; 68G; 99; 44G | |||||||||||
| NTIS Prices | PC A03/MF A03 | |||||||||||
| Document Type | NT | |||||||||||
| Cataloging Source | NTIS/MT | |||||||||||
| Control Number | 028802110 | |||||||||||
| Origin | NTIS | |||||||||||
| Type | CAT |