| Main Title |
Initial Submission: 28-Day Repeated Dose Oral (Gavage) Toxicity Study in the Rats with (Confidential), with Cover Letter dated 05/27/1999. (Sanitized). |
| CORP Author |
Safepharm Laboratories, Ltd., Princeton, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1999 |
| Stock Number |
OTS0573924 |
| Additional Subjects |
Toxicology ;
Health effects ;
Oral ;
Gavage ;
Rats ;
Mammals ;
Acute toxicity ;
CAS No 110-62-3
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0573924 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
301p |
| Abstract |
The study was designed to investigate the systemic toxicity of the test material and complies with the Japanese Ministry of Health and Welfare (MHW) Guidelines 1986 for a twenty-eight day repeat dose oral toxicity study as required by the Japanese Chemical Substances Control Law 1973 of the Ministry of International Trade and Industry (MITI) amended 1986. The test material was administered by gavage to three groups, each of five male and five female Sprague-Dawley Crl:CD-BR strain rats, for twenty-eight consecutive days, at dose levels of 15, 150 and 500 mg/kg/day. A control group of five males and five females was dosed with vehicle alone (Arachis oil BP). Two recovery groups, each of five males and five females, were treated with the high dose (500 mg/kg/day) or the vehicle alone for twenty-eight consecutive days and then maintained without treatment for a further fourteen days. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1 Jun 1999 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A15/MF A15 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028702190 |
| Origin |
NTIS |
| Type |
CAT |
