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Main Title Evaluation of the potential carcinogenicity of amitrole (61-82-5) /
CORP Author Syracuse Research Corp., NY. ;Environmental Monitoring and Services, Inc., Washington, DC.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher U.S. Environmental Protection Agency, Office of Emergency and Remedial Response ;
Year Published 1988
Report Number EPA/600/8-91/060; EPA-68-03-3112; EPA-68-03-3182; OHEA-C-073-004
Stock Number PB93-181659
Subjects Aromatic compounds--Carcinogenicity ; Amitrole--Carcinogenicity
Additional Subjects Carcinogens ; Toxicity ; Amitrole ; Humans ; Animals ; Dose-response relationships ; Carcinogenicity tests ; CAS 61-82-5
Library Call Number Additional Info Location Last
NTIS  PB93-181659 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 20 pages ; 28 cm
Abstract Amitrole is a probable human carcinogen, classified as weight-of-evidence Group B2 under the EPA Guidelines for Carcinogen Risk Assessment. Evidence on potential carcinogenicity from animal studies is 'sufficient,' and the evidence from human studies is 'inadequate.' The potency factor (F) for amitrole is estimated to be 3.30/(mg/kg/day), placing it in potency group 2 according to the CAG's methodology for evaluating potential carcinogens. Combining the weight-of-evidence group and the potency group, amitrole is assigned a 'MEDIUM' hazard ranking for the purposes of RQ adjustment.
Notes Cover title. "June 1988." Includes bibliographical references. Microfiche.
Place Published Washington, D.C. :
Supplementary Notes See also PB-223 159. Prepared in cooperation with Environmental Monitoring and Services, Inc., Washington, DC. Sponsored by Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Corporate Au Added Ent United States. Environmental Protection Agency. Office of Health and Environmental Assessment. Carcinogen Assessment Group.
PUB Date Free Form {1988}
NTIS Prices PC A03/MF A01
BIB Level m
Cataloging Source OCLC/T
OCLC Time Stamp 20010328134317
Language eng
Origin NTIS
OCLC Rec Leader 01186nam 2200265Ka 45020