| Main Title |
Compartmental Models with Spatial Diffusion: Estimation for Bone-Seeking Tracers. |
| Author |
Marcus, A. H. ;
|
| CORP Author |
Washington State Univ., Pullman. Dept. of Pure and Applied Mathematics.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1983 |
| Report Number |
EPA/600/J-83/343; |
| Stock Number |
PB86-208816 |
| Additional Subjects |
Models ;
Bones ;
Diffusion ;
Isotopic labeling ;
Reprints ;
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB86-208816 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
19p |
| Abstract |
A compartmentlike model is developed for tracers in which bone-volume diffusion plays an important role in body distribution (e.g. bone-volume-seeking metals). The model requires solution of an infinite eigensystem. Approximations are presented for cylindrical diffusion in canalicular territory. An application to lead metabolism in beagle dogs suggests that finite truncation of the system of equations provides an adequate approximation for routine use in computer programs for compartmental-parameter estimation. The model is consistent with both power-law and exponential mixture retention functions. |
| Supplementary Notes |
Pub. in Mathematical Biosciences 64, p238-248 1983. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Compartmental Models with Spatial Diffusion: Estimation for Bone-Seeking Tracers. |
| PUB Date Free Form |
c1983 |
| Category Codes |
6B; 95C |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
622718576 |
| Origin |
NTIS |
| Type |
CAT |
