Main Title |
Effects of low level carbon monoxide exposure : blood lipids and coagulation parameters / |
Author |
Brinkhous, K. M. ;
Brinkhouse., K. M.
|
CORP Author |
North Carolina Univ., Chapel Hill. Dept. of Pathology.;Health Effects Research Lab., Research Triangle Park, N.C. |
Publisher |
U.S. Environmental Protection Agency, Health Effects Research Laboratory, |
Year Published |
1977 |
Report Number |
EPA/600/1-77/032; EPA-68-02-1281 |
Stock Number |
PB-269 340 |
OCLC Number |
42838161 |
Subjects |
Carbon monoxide--Physiological effect
|
Additional Subjects |
Carbon monoxide ;
Toxicity ;
Blood coagulation ;
Lipids ;
Dosage ;
Exercise(Physiology) ;
Fibrin ;
Blood ;
Concentration(Composition) ;
Males ;
Experimental data ;
Exposure ;
Physiological effects ;
Cholesterol ;
Glycerides ;
Hematocrit ;
Platelets ;
Prothrombin ;
Thromboplastin ;
Thrombin ;
Cigarette smoking ;
Carbonylhemoglobin ;
Air pollution effects(Humans) ;
Blood coagulation factor VIII ;
Environmental health
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EJBD |
EPA 600-1-77-032 |
c.1 |
Headquarters Library/Washington,DC |
05/27/2014 |
EJED |
EPA 600/1-77/032 |
|
OCSPP Chemical Library/Washington,DC |
07/01/2005 |
EKBD |
EPA-600/1-77-032 |
|
Research Triangle Park Library/RTP, NC |
06/06/2003 |
ELBD ARCHIVE |
EPA 600-1-77-032 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
ELBD |
EPA 600-1-77-032 |
|
AWBERC Library/Cincinnati,OH |
09/02/2016 |
NTIS |
PB-269 340 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
iv, 23 pages ; 28 cm. |
Abstract |
The study examined the effects of carbon monoxide (CO) in 50 and 100 ppm doses on response to treadmill exercise, blood coagulation and blood lipids in normal men. Twenty-three men were exposed to CO or to air in a double-blind protocol. After exposure, each underwent a graded exercise treadmill test which was terminated at 85% maximal heart rate. Blood for measurement of carboxyhemoglobin (COHb), hematocrit, platelet count, prothrombin time, partial thromboplastin time, thrombin time, fibrin split products, factor VIII, platelet aggregation, serum cholesterol and triglycerides was drawn at baseline, preexercise and postexercise. COHb did not change on air days but reached a mean of 2.17% on 50 ppm days and 4.15% on 100 ppm days. The mean duration of exercise was 19 sec shorter on CO days than on air days (f = 4.93). The greatest effect was on 100 ppm days (f = 8.00). Coagulation parameters and cholesterol and triglyceride measurements were not significantly affected by CO exposure. |
Notes |
"EPA-600/1-77-032." EPA contract no. 68-02-1281; EPA project officer: Edward D. Haak, Jr. |
Place Published |
Research Triangle Park, NC |
Access Notes |
Also available via the World Wide Web. |
Corporate Au Added Ent |
Health Effects Research Laboratory (Research Triangle Park, N.C.); United States. Environmental Protection Agency. Office of Research and Development.; University of North Carolina (System). Department of Pathology. |
Title Ser Add Ent |
Research reporting series. Environmental health effects research ; EPA 600/1-77/032. |
PUB Date Free Form |
June 1977 |
Series Title Untraced |
Environmental health effects research series ; EPA 600/1-77/032 |
Category Codes |
6T; 6F; 13B; 57Y; 68G; 68A |
NTIS Prices |
PC A03/MF A01 |
Primary Description |
600/11 |
BIB Level |
m |
Medium |
unmediated |
Content |
text |
Carrier |
volume |
Cataloging Source |
OCLC/T |
Control Number |
323720648 |
OCLC Time Stamp |
20160826062720 |
Language |
eng |
Origin |
OCLC |
Type |
MERGE |
OCLC Rec Leader |
01895cam 2200445Ka 45010 |