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OLS Field Name OLS Field Data
Main Title Single Cell Sequencing and Systems Immunology [electronic resource] /
Other Authors
Author Title of a Work
Wang, Xiangdong.
Publisher Springer Netherlands : Imprint: Springer,
Year Published 2015
Call Number QR180-189.5
ISBN 9789401797535
Subjects Medicine. ; Immunology. ; Proteomics. ; Biological models. ; Cytology.
Internet Access
Description Access URL
Collation XI, 177 p. 89 illus., 62 illus. in color. online resource.
Notes Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes Preface -- Significance of Single Cell Sequencing in Future Medicine -- Uncovering Phenotypes with Supercells: Applications to Single-Cell Sequencing -- Single-Cell Sequencing of Microorganisms -- Application of single-cell sequencing in dynamic transcriptomes -- System Immunology in Metabolic Research of Dendritic Cells -- FOXP3+ Treg Cells and Systems Biology Approaches to Studying Their Function -- γδT Cells and αβT Cells -- Prolymphocyte: Lymphocytes and Bioinformatics -- Lymphocytes in liver cancer -- Early biomarkers of hepatocyte necrosis -- Protocol of Single Cell Isolation by Flow Cytometry -- Single-cell based omics-the new era of human disease and medicine -- Cancer bioinformatics. . The volume focuses on the genomics, proteomics, metabolomics, and bioinformatics of a single cell, especially lymphocytes and on understanding the molecular mechanisms of systems immunology. Based on the author's personal experience, it provides revealing insights into the potential applications, significance, workflow, comparison, future perspectives and challenges of single-cell sequencing for identifying and developing disease-specific biomarkers in order to understand the biological function, activation and dysfunction of single cells and lymphocytes and to explore their functional roles and responses to therapies. It also provides detailed information on individual subgroups of lymphocytes, including cell characters, function, surface markers, receptor function, intracellular signals and pathways, production of inflammatory mediators, nuclear receptors and factors, omics, sequencing, disease-specific biomarkers, bioinformatics, networks and dynamic networks, their role in disease and future prospects. Dr. Xiangdong Wang is a Professor of Medicine, Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Director of the Biomedical Research Center of Zhongshan Hospital, Deputy Director of Shanghai Respiratory Research Institute, Shanghai, China. .
Place Published Dordrecht
Corporate Au Added Ent SpringerLink (Online service)
Title Ser Add Ent Translational Bioinformatics, 5
Host Item Entry Springer eBooks
PUB Date Free Form 2015
Series Title Untraced Translational Bioinformatics, 5
BIB Level m
Medium computer
Content text
Carrier online resource
Cataloging Source OCLC/T
OCLC Time Stamp 20150521140938
Language eng
OCLC Rec Leader 03663nam a22004935i 45