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OLS Field Name OLS Field Data
Main Title Handbook on Analyzing Human Genetic Data Computational Approaches and Software / [electronic resource] :
Author Lin, Shili.
Other Authors
Author Title of a Work
Zhao, Hongyu.
Publisher Springer Berlin Heidelberg,
Year Published 2010
Call Number QH431
ISBN 9783540692645
Subjects Medicine. ; Human genetics. ; Bioinformatics. ; Genetics--Mathematics. ; Mathematical statistics.
Internet Access
Description Access URL
Collation XIV, 333 p. online resource.
Notes Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes Population Genetics -- Haplotype Structure -- Linkage Analysis of Qualitative Traits -- Linkage Analysis of Quantitative Traits -- Markov Chain Monte Carlo Linkage Analysis Methods -- Population-Based Association Studies -- Family-Based Association Studies -- Haplotype Association Analysis -- Multiple Comparisons/Testing Issues -- Estimating the Absolute Risk of Disease Associated with Identified Mutations -- Processing Large-Scale, High-Dimension Genetic and Gene Expression Data. The discipline of statistical genetics is highly computational. Be it exact computational methods, simulation based, or a hybrid of the two, computational packages are indispensable tools and constant companions of researchers in the field. This handbook is intended to provide human geneticists and other biomedical researchers with guidance on selections of appropriate computational methods and software packages for their specific genetic problems. It may also be used by students and other learners as a reference in conjunction with a more theoretical and/or methodologically oriented text book. This book tries to strike a balance between methodological expositions and practical guidelines for software selections. Wherever possible, comparisons among competing methods and software are made to highlight the relative advantages and disadvantage of the approaches so that the readers can make informed choices to best match their specific needs.
Place Published Berlin, Heidelberg
Corporate Au Added Ent SpringerLink (Online service)
Host Item Entry Springer eBooks
PUB Date Free Form 2010
BIB Level m
Medium computer
Content text
Carrier online resource
Cataloging Source OCLC/T
OCLC Time Stamp 20141127192408
Language eng
OCLC Rec Leader 03221nam a22005415i 45