| Main Title |
Support: Letter from Dupont Haskell Laboratory to USEPA re: Results of 90-Day Subchronic Feeding Study in Mice of P-901840, dated 04/24/2000. |
| CORP Author |
Du Pont de Nemours (E.I.) and Co., Wilmington, DE. Haskell Lab. for Toxicology and Industrial Medicine.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
2000 |
| Report Number |
8EHQ-0400-0898 |
| Stock Number |
OTS0524003-6 |
| Additional Subjects |
Toxicology ;
Health effects ;
Butoxytriglycol ;
Acute toxicity ;
Environmental fate ;
Biodegradation ;
Environmental effects ;
Bacteria ;
Freshwater fish ;
Invertebrates ;
CAS No 143-22-6 ;
CAS No 112-35-6 ;
CAS No 112-50-5 ;
CAS No 122-99-6 ;
CAS No 124-17-4
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0524003-6 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
7p |
| Abstract |
Groups of 10 female Cri:CD-1(ICR)BR mice were fed diets containing 0, 20, 100, 500, or 1000 ppm of the test substance. Groups of 10 male Crl:CD-1 (ICR)BR mice were fed diets containing 0, 20, 100, 500, or 2000 ppm of the test substance. After approximately 8 weeks of feeding, the 2000 ppm dose level was reduced to 1000 ppm, due to mortality, for the remainder of the study. Equivalent mean daily intakes were 0, 3.2, 15, 78, or 320/166 mg/kg for males and 0, 4.2, 20, 104, or 228 mg/kg for females. Body weights, food consumption, and clinical observations were evaluated weekly. Cage-side examinations for mortality were performed daily. After 13 weeks of dietary exposure, all surviving mice were necropsied. A gross and microscopic examination was performed. On all surviving animals and animals found dead or sacrificed in extremis. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Sponsored by Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5301 Shawnee Road, Alexandria, VA, 22312, USA. |
| PUB Date Free Form |
24 Apr 2000 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A02/MF A02 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
100700130 |
| Origin |
NTIS |
| Type |
CAT |
