| Main Title |
Poly(ADP-Ribosyl)ation [electronic resource] / |
| Type |
EBOOK |
| Author |
Bürkle, Alexander.
|
| Publisher |
Springer US, |
| Year Published |
2006 |
| Call Number |
QR46 |
| ISBN |
9780387360058 |
| Subjects |
Medicine ;
Human genetics ;
Microbiology ;
Biochemistry ;
Cytology
|
| Internet Access |
|
| Collation |
XVII, 246 p. online resource. |
| Notes |
Due to license restrictions, this resource is available to EPA employees and authorized contractors only |
| Contents Notes |
Enzymes in Poly(ADP-Ribose) Metabolism -- PARP-2: Structure-Function Relationship -- Targeting the Poly (ADP-Ribose) Glycohydrolase (PARG) Gene in Mammals -- DNA Damage Signaling through Poly(ADP-Ribose) -- Roles of Poly(ADP-Ribose) Metabolism in the Regulation of Centrosome Duplication and in the Maintenance of Neuronal Integrity -- Functional Interactions of PARP-1 with p53 -- Dynamic Interaction between PARP-1, PCNA and p21waf1/cip1 -- PARP-1 as Novel Coactivator of NF-?B in Inflammatory Disorders -- PARP and Epigenetic Regulation -- PARP and the Release of Apoptosis-Inducing Factor from Mitochondria -- Genome Degradation by DNAS1L3 Endonuclease -- NAD: Metabolism and Regulatory Functions -- PARP-1 and the Shape of Cell Death -- Poly(ADP-Ribose) Polymerase (PARP) and Excitotoxicity -- Poly(ADP-Ribose) Polymerase and Ischemia-Reperfusion Injury -- Role of Poly(ADP-Ribose) Polymerase Activation in the Pathogenesis of Inflammation and Circulatory Shock -- Role of Poly-ADP-Ribosylation in Cancer Development -- PARP Inhibitors and Cancer Therapy -- Poly(ADP-Ribosyl)ation and Aging. Poly(ADP-Ribosyl)ation comprises 19 chapters written by leading international experts in the field and is richly illustrated. Extensive bibliography is given in each chapter. |
| Place Published |
Boston, MA |
| Corporate Au Added Ent |
SpringerLink (Online service) |
| Title Ser Add Ent |
Molecular Biology Intelligence Unit |
| Host Item Entry |
Springer eBooks |
| PUB Date Free Form |
2006 |
| Series Title Untraced |
Molecular Biology Intelligence Unit |
| BIB Level |
m |
| Medium |
computer |
| Content |
text |
| Carrier |
online resource |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
20131219115954 |
| Language |
eng |
| Origin |
SPRINGER |
| Type |
EBOOK |
| OCLC Rec Leader |
02771nam a22004935i 45 |
