| Main Title |
Metabolism of carbamate insecticides / |
| Author |
Dorough, H. W.
|
| CORP Author |
Kentucky Univ., Lexington. Dept. of Entomology.;Health Effects Research Lab., Research Triangle Park, N.C. |
| Publisher |
Environmental Sciences Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, |
| Year Published |
1977 |
| Report Number |
EPA-600/1-77-012; EPA-R-802005 |
| Stock Number |
PB 266 223 |
| OCLC Number |
52399418 |
| Subjects |
Carbamates ;
Pesticides
|
| Additional Subjects |
Insecticides ;
Pesticides ;
Carbamates ;
Esters ;
Metabolism ;
Hydrolysis ;
Laboratory animals ;
Domestic animals ;
Plants(Botany) ;
Food chains ;
Toxicology ;
Carcinogens ;
In vitro analysis ;
In vivo analysis ;
Biochemistry ;
Physiology ;
Glutathione ;
Metabolites ;
Pesticide residues ;
Mutagens ;
Ames mutagenic assay system
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EJBD |
EPA 600-1-77-012 |
|
Headquarters Library/Washington,DC |
01/17/2014 |
| EKBD |
EPA-600/1-77-012 |
|
Research Triangle Park Library/RTP, NC |
06/20/2003 |
| ELBD ARCHIVE |
EPA 600-1-77-012 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
| ELBD |
EPA 600-1-77-012 |
|
AWBERC Library/Cincinnati,OH |
12/26/2017 |
| ERAD |
EPA 600/1-77-012 |
|
Region 9 Library/San Francisco,CA |
06/11/2012 |
| NTIS |
PB-266 223 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
244 pages : illustrations ; 28 cm. |
| Abstract |
The results of studies conducted to determine the metabolic fate of carbamate insecticides and its toxicological significance are presented. Methomyl metabolism in rats was investigated in detail as was Croneton in the rat, cow, pig and chicken. Carbaryl and carbofuran were administered to rats endotracheally either as aerosols or as components of tobacco smoke and their fate determined. Carbaryl and nitrosocarbaryl were among a series of pesticides assayed for mutagenic/carcinogenic activity using the Ames assay system. In addition, a study was conducted to determine if the in vitro metabolism of carbaryl under conditions of the Ames assay was representative of that which occurs in vivo. Respiratory 14C-carbon dioxide from carbonyl-labeled carbamates was evaluated as a technique for determining the effects of various factors on the metabolism of carbamate insecticides. Carbaryl and certain of its analogs were used in studies designed to define the role of glutathione conjugation in carbamate metabolism in rats. Conjugate and bound residues of carbaryl, carbofuran, Croneton and aldicarb formed by plants were administered orally to rats and their bioavailability ascertained. |
| Notes |
EPA-600/1-77-012. "February 1977." Includes bibliographical references (pages 226-235). |
| Place Published |
Research Triangle Park, NC |
| Supplementary Notes |
See also PB-231 596. |
| Corporate Au Added Ent |
United States. Environmental Protection Agency. Office of Research and Development.; Environmental Sciences Research Laboratory. |
| Title Ser Add Ent |
Ecological health effects research series. |
| PUB Date Free Form |
1977 |
| Series Title Traced |
Ecological health effects research series |
| Series Title Untraced |
Ecological health effects research series |
| NTIS Prices |
PC A12/MF A01 |
| BIB Level |
m |
| Medium |
unmediated |
| Content |
text |
| Carrier |
volume |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
20171222060500 |
| Language |
eng |
| SUDOCS Number |
EP 1.23/4:600/1-77-012 |
| Origin |
OCLC |
| Type |
MERGE |
| OCLC Rec Leader |
01783cam 2200469Ka 45010 |
