Main Title |
Initial Submission: Summary of Toxicokinetic Studies on Bis(Tributyltin) Oxide (TBTO) Performed at Schering with Cover Letter dated 09/29/1992. |
CORP Author |
Schering AG.; Elf Atochem North America, Philadelphia, PA.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
Year Published |
1992 |
Report Number |
8EHQ-1092-11345 |
Stock Number |
OTS0571283 |
Additional Subjects |
Toxicology ;
Health effects ;
Tributyltin oxide ;
Acute toxicity ;
Mammals ;
Rabbits ;
Parenteral ;
Intraperitoneal ;
Monkeys ;
Dermal ;
Pharmaco kinetics ;
Biochemistry ;
Tissue concentration ;
CAS No 56-35-9
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Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
OTS0571283 |
Some EPA libraries have a fiche copy filed under the call number shown. |
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07/26/2022 |
|
Collation |
33p |
Abstract |
Four groups of each 5 male rats received a daily dose of 5 mg TBTO/kg as aqueous suspension once, three times, 7 times, and 14 times, respectively. Organ and tissue specimens were removed in each case 24 hours after the single (last) dose. Urine and feces were collected in daily frac- tions in that group of animals treated for 14 days. As was shown by a preexperiment in bile duct cannulated animals only about 20 % of TBTO dose administered was absorbed in this study. Excluding the radioactivity located in the gastro-intestinal tract (GIT), on an average 12 + or - 2 % of the administered dose was detectable in the animal bodies 24 hours after i.g. administration. |
Supplementary Notes |
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Availability Notes |
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PUB Date Free Form |
13 Oct 1992 |
Category Codes |
57Y; 57U; 68G; 99; 44G |
NTIS Prices |
PC A04/MF A04 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
018802100 |
Origin |
NTIS |
Type |
CAT |