| Main Title |
Glycans in Diseases and Therapeutics [electronic resource] / |
| Type |
EBOOK |
| Author |
Pavão, Mauro S.G.
|
| Publisher |
Springer Berlin Heidelberg, |
| Year Published |
2011 |
| Call Number |
QH573-671 |
| ISBN |
9783642168338 |
| Subjects |
Life sciences ;
Human physiology ;
Medicine ;
Biochemistry ;
Cytology
|
| Internet Access |
|
| Collation |
XII, 188 p. online resource. |
| Notes |
Due to license restrictions, this resource is available to EPA employees and authorized contractors only |
| Contents Notes |
Heparan Sulfate Proteoglycan in Inflammation and Angiogenesis -- Heparan Sulfate Proteoglycans in Infection -- Glycans in cancer -- Glycosaminoglycans in atherosclerosis and thrombosis -- Glycans in Embryonic Stem Cells -- Heparan sulfate proteoglycans in cancer progression and therapy -- Structure and biological activities of glycosaminoglycan analogs from marine invertebrates: new therapeutic agents?. Initially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions. This volume of the series "Biology of Extracellular Matrix" reviews the most recent findings on the role of glycans in the development of diseases and the possible therapeutic use of this class of molecules. It shows how the interaction of glycans with growth factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and adhesive proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic stem cell biology. Furthermore, an extensive survey about the structure and pharmacological effects of unique marine glycosaminoglycans is discussed as well as the possibility of using these glycans as therapeutic agents. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology. |
| Place Published |
Berlin, Heidelberg |
| Corporate Au Added Ent |
SpringerLink (Online service) |
| Title Ser Add Ent |
Biology of Extracellular Matrix |
| Host Item Entry |
Springer eBooks |
| PUB Date Free Form |
2011 |
| Series Title Untraced |
Biology of Extracellular Matrix |
| BIB Level |
m |
| Medium |
computer |
| Content |
text |
| Carrier |
online resource |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
20130725205757 |
| Language |
eng |
| Origin |
SPRINGER |
| Type |
EBOOK |
| OCLC Rec Leader |
03033nam a22004935i 45 |
