| Main Title |
Change in the DNA Content of the Nuclei of Tumor Cells in the Process of 'Progression' of the Induced Hepatoma (Izmenenie Soderzhaniya DNK v Yadrakh Opukholevykh Kletok v Protesse 'Progressii' Indutsirovannoi Hepatomy). |
| Author |
Pozharisskii, K. M. ;
Shalumovich, V. N. ;
Shaposhnikov., Ya. D. ;
|
| CORP Author |
Environmental Protection Agency, Research Triangle Park, N.C. Translation Services Section. |
| Year Published |
1973 |
| Report Number |
EPA-TR-76-31; |
| Stock Number |
PB-259 072-T |
| Additional Subjects |
Neoplasms ;
Deoxyribonucleic acids ;
Cytochemistry ;
Cells(Biology) ;
Biochemistry ;
Nucleic acids ;
Liver ;
USSR ;
Translations ;
Carcinogenesis
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-259 072-T |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
16p |
| Abstract |
Biochemical and cytophotometric investigations have shown that the DNA content of tumors increased in comparison with the homologic normal tissues and that authors who have conducted investigations using cytophotometric methods have detected a direct correlation between the amount of DNA in the nuclei of tumor cells and the degree of the differentiation. Thus, with the increase in the duration of effect of a blastomogenic agent on animals, the relative amount of polyploid cells increases in the liver. At the same time, it was established that the DNA content of hepatic cells increases in the process of carcinogenesis in this organ. The indicated studies were devoted to an investigation of the DNA content in the nuclei of tumor cells or cells in the stage of malignization, and, therefore, the final stage of the investigation was the formed tumor. |
| Supplementary Notes |
Trans. of Voprosy Onkologii (USSR) v19 n3 p73-80 1973.(PC A02/MF A01) |
| Title Annotations |
+++Change in the DNA Content of the Nuclei of Tumor Cells in the Process of 'Progression' of the Induced Hepatoma (Izmenenie Soderzhaniya DNK v Yadrakh Opukholevykh Kletok v Protesse 'Progressii' Indutsirovannoi Hepatomy)--Translation. |
| PUB Date Free Form |
1973 |
| Category Codes |
6A; 6E; 57F; 57O |
| NTIS Prices |
PC A02/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
323702873 |
| Origin |
NTIS |
| Type |
CAT |
