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Main Title Drug Metabolism and Pharmacokinetics Quick Guide [electronic resource] /
Type EBOOK
Author Khojasteh, Siamak Cyrus.
Other Authors
Author Title of a Work
Wong, Harvey.
Hop, Cornelis E.C.A.
Publisher Springer New York,
Year Published 2011
Call Number RM1-950
ISBN 9781441956293
Subjects Medicine ; Toxicology ; Pharmacy ; Biochemistry
Internet Access
Description Access URL
http://dx.doi.org/10.1007/978-1-4419-5629-3
Collation XIII, 214 p. online resource.
Notes Due to license restrictions, this resource is available to EPA employees and authorized contractors only
Contents Notes Pharmacokinetics -- Drug Metabolizing Enzymes -- Oral Absorption -- Transporters -- Metabolism-Based Drug Interactions -- Biotransformation and Bioactivation -- Prediction of Human Pharmacokinetics -- Advances in Bioanalysis as it Relates to ADME -- ADME Properties and Their Dependence on Physicochemical Properties -- In Silico ADME Tools -- Approved Drugs -- Chemical Nomenclature. Drug Metabolism and Pharmacokinetics Quick Guide is intended for broad readership of those interested in the discipline of drug metabolism and pharmacokinetics who work in drug discovery coming from the various disciplines, a background such as of medicinal chemistry, pharmacology, drug metabolism and pharmacokinetics, bioanalysis, clinical sciences, biochemistry, pharmaceutics or toxicology. This guide provides, for the first time, a completely integrated look at multiple aspects of absorption, distribution, metabolism, and excretion (ADME) science in a summary format that is clear, concise and self-explanatory. This book will be used and referenced frequently as it provides detailed figures and tables for data interpretation. Also included are brief yet relevant factoids that bring a real-world dimension to the discussion of drug metabolism and pharmacokinetics. Key topics covered: 1. Pharmacokinetics 2. Drug metabolizing enzymes 3. Oral absorption 4. Transporters 5. Metabolism-based drug interactions 6. Biotransformation and bioactivation 7. Prediction of human pharmacokinetics 8. Bioanalysis 9. Physicochemical properties and drug-like properties 10. In silico tools 11. Approved drugs 12. Chemical nomenclature
Place Published New York, NY
Corporate Au Added Ent SpringerLink (Online service)
Host Item Entry Springer eBooks
PUB Date Free Form 2011
BIB Level m
Medium computer
Content text
Carrier online resource
Cataloging Source OCLC/T
OCLC Time Stamp 20140202091916
Language eng
Origin SPRINGER
Type EBOOK
OCLC Rec Leader 03114nam a22004695i 45