Full Record Display for the EPA National Library Catalog

RECORD NUMBER: 317 OF 864

Main Title Effect of duck hepatitis virus on pesticide toxicity /
Author Ragland, William Lauman, ; Ragland., W. L.
CORP Author Georgia Univ., Athens. Poultry Disease Research Center.;Health Effects Research Lab., Research Triangle Park, N.C.
Publisher U.S. Environmental Protection Agency, Health Effects Research Laboratory,
Year Published 1976
Report Number EPA-600/1-76-003; EPA-R801800
Stock Number PB-249 351
OCLC Number 42786718
Subjects Virology--Research ; DDT (Insecticide)--Research ; Newcastle disease vaccine
Additional Subjects Enzymes ; Liver ; Pesticides ; Hepatitis viruses ; Metabolism ; Induction ; Reticuloendothelial system ; DDT ; Tissues(Biology) ; Ducks ; Newcastle disease virus ; Drugs ; Bioaccumulation ; Pesticide residues
Internet Access
Description Access URL
https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=9101387G.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
EJBD  EPA 600-1-76-003 Headquarters Library/Washington,DC 01/17/2014
EKBD  EPA-600/1-76-003 Research Triangle Park Library/RTP, NC 02/11/2000
ELBD ARCHIVE EPA 600-1-76-003 Received from HQ AWBERC Library/Cincinnati,OH 10/04/2023
ELBD  EPA 600-1-76-003 AWBERC Library/Cincinnati,OH 11/15/2016
NTIS  PB-249 351 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation viii, 63 pages ; 28 cm.
Abstract The report presents the results of an investigation into the effect of viral replication on hepatic endoplasmic reticulum on the activities of the microsomal drug-metabolizing enzymes of liver. Two viruses which replicate on hepatic endoplasmic reticulum without producing hepatic disease were used. They were Newcastle disease vaccinal virus in chickens and duck hepatitis virus in adult ducks. The microsomal enzymes assayed were ethylmorphine N-demethylase, aryl hydrocarbon hydroxylase and anyline hydroxylase. The soluble enzyme, nitroreductase, also was assayed in chickens. Pesticide residue analysis was used to evaluate indirectly the microsomal enzymatic conversion of DDT to DDD and the soluble enzymatic conversion of DDT to DDE in ducks. Viral replication did not increase the activities of the microsomal enzymes and may have decreased the activities slightly. Although the microsomal enzymes were induced to greater levels by viral replication, pesticide residue analysis failed to demonstrate increased clearance of residues from body tissues.
Notes "EPA-600/1-76-003." EPA grant no. R801800; EPA project officer: Ronald L. Baron. Includes bibliographical references (pages 59-61).
Place Published Research Triangle Park, NC
Access Notes Also available via the World Wide Web.
Corporate Au Added Ent Health Effects Research Laboratory (Research Triangle Park, N.C.); United States. Environmental Protection Agency. Office of Research and Development.; University of Georgia. Poultry Disease Research Center.
Title Ser Add Ent Research reporting series. Environmental health effects research ; EPA-600/1-76-003.
NTIS Title Notes Final rept..
PUB Date Free Form January 1976
Series Title Untraced Environmental health effects research series ; EPA 600/1-76/003
Category Codes 06A; 06T; 57B; 57Y
NTIS Prices PC A04/MF A01
BIB Level m
Medium unmediated
Content text
Carrier volume
Cataloging Source OCLC/T
Control Number 326613632
OCLC Time Stamp 20161028072911
Language eng
Origin OCLC
Type MERGE
OCLC Rec Leader 02148cam 2200517Ka 45010