||Guidance for Safety Testing of Baculoviruses.
||Environmental Protection Agency, Washington, D. C.
||PB-280 566; PB-280 565
Insect control ;
Pest control ;
Experimental design ;
Respiratory system ;
DNA viruses ;
Insect viruses ;
Biological pest control ;
Biological insect control ;
||Some EPA libraries have a fiche copy filed under the call number shown.
||The following guidance summarizes the data presently required by the Agency to show the safety of nuclear polyhedrosis and granulosis virus insecticides. (These two groups of insect viruses in the following are referred to as 'virus' or 'insect virus.') When testing the safety of insect viruses, primary emphasis must be given to their pathogenicity and not to their toxicity. Pathogenicity is the capability of the microorganism to infect or reproduce, or to cause overt or covert changes, in animals or animal tissue other than target insects. Toxicity means that microorganisms, and/or their by-products, harm the test animal without actual multiplication such as in certain adverse immunological reactions.
||Included in PB-280 565, Journal articles on toxicology. Group 12.
||Pub. in Baculoviruses for Insect Pest Control: Safety Considerations, 1975.
||Included in the report, Journal Articles on Toxicology, Group 12, PB-280 565.
||Journal articles on toxicology. Group 12.
||Reprint: Guidance for Safety Testing of Baculoviruses.
|PUB Date Free Form
||6K; 57M; 57P
||(Order as PB-280 565, MF A01)