| Main Title |
Catabolism of Aromatic Biogenic Amines by 'Pseudomonas aeruginosa' PA01 via meta Cleavage of Homoprotocatechuic Acid (Journal Version). |
| Author |
Cuskey, S. M. ;
Olsen, R. H. ;
|
| CORP Author |
Environmental Research Lab., Gulf Breeze, FL. ;Michigan Univ., Ann Arbor. Medical School. |
| Publisher |
c1988 |
| Year Published |
1988 |
| Report Number |
EPA/600/J-88/109; |
| Stock Number |
PB89-120067 |
| Additional Subjects |
Biogenic amines ;
Pseudomonas aruginosa ;
Metabolism ;
Bacteria ;
Tyramine ;
Oxygenases ;
NADH ;
NADPH oxidoreductases ;
Analklyamines ;
Mutations ;
Enzyme induction ;
Molecular cloning ;
Chromosome mapping ;
Reprints ;
Octopamine ;
Benzene methanol/(aminomethyl)-hydroxy
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB89-120067 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
8p |
| Abstract |
Pseudomonas aruginosa PA01 catabolized the aromatic amines tyramine and octopamine through 4-hydroxyphenylacetic acid and 3,4-dihydroxyphenylacetic acid (HPA). Meta ring cleavage was mediated by 3-4-dihydroxyphenylacetate 2,3-dioxygenase (HPADO), producing 2-hydroxy-5-carboxymethylmuconic semialdehyde (MSA). An NAD-dependent dehydrogenase caused the disappearance of the yellow MSA product, probably forming 2-hydroxy-5-carboxymethylmuconic acid. Induction studies with extracts from mutant cells indicated that the inducer of HPADO was HPA and/or MSA. Strains PA01.221 (tynCl) and PA01.303 (tynDI) have chromosomal mutations causing a deficiency in the activity necessary for conversion of 4-hydroxyphenylacetic acid to HPA. (Copyright (c) 1988 American Society for Microbiology.) |
| Supplementary Notes |
Prepared in cooperation with Michigan Univ., Ann Arbor. Medical School. |
| Availability Notes |
Pub. in Jnl. of Bacteriology, v170 n1 p393-399 Jan 88. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Catabolism of Aromatic Biogenic Amines by 'Pseudomonas aeruginosa' PA01 via meta Cleavage of Homoprotocatechuic Acid (Journal Version). |
| Category Codes |
57K; 57B; 57F |
| NTIS Prices |
Not available NTIS |
| Primary Description |
600/04 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
901217419 |
| Origin |
NTIS |
| Type |
CAT |
