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RECORD NUMBER: 185 OF 2019

Main Title Bacterial Reverse Mutation Assay using Vapor-Phase Exposure for 1,6-Hexamethylene Diisocyanate, with Cover Letter dated 09/20/1998.
CORP Author Microbiological Associates, Bethesda, MD.; Chemical Manufacturers Association, Washington, DC.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1999
Stock Number OTS0573907
Additional Subjects Toxicology ; Health effects ; 1 ; 6-hexamethylene diisocyante ; Genotoxicity ; Gene mutations ; Bacteria ; In vitro ; CAS No 822-06-0
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NTIS  OTS0573907 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 68p
Abstract The test substance, 1,6 - hexamethylene diisocyanate, was tested in the bacterial reverse mutation assay using S. typhimwium tester strains TA98, TA100, TA1535 and TA1537 in the presence and absence of Aroclor-induced rat liver S9. The assay was performed in two phases, using the vapor-phase exposure method. The first phase, the preliminary toxicity assay, was used to establish the dose range for the mutagenicity assay. The second phase, the mutagenicity assay, was used to evaluate the mutagenic potential of the test substance.
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PUB Date Free Form 29 Jan 1999
Category Codes 57Y; 57U; 68G; 99; 44G
NTIS Prices PC A05/MF A05
Document Type NT
Cataloging Source NTIS/MT
Control Number 028702030
Origin NTIS
Type CAT