| Main Title |
Drinking Water Criteria Document for Antimony. |
| CORP Author |
Dynamac Corp., Rockville, MD.;Environmental Protection Agency, Washington, DC. Office of Drinking Water. |
| Publisher |
Apr 90 |
| Year Published |
1990 |
| Stock Number |
PB90-215435 |
| Additional Subjects |
Potable water ;
Toxicology ;
Water quality ;
Antimony ;
Mutagens ;
Carcinogens ;
Reproduction(Biology) ;
Lethal dosage ;
Exposure ;
Laboratory animals ;
Body weight ;
Enzymes ;
Enzyme inhibitors ;
Dose-response relationships ;
Pharmacokinetics ;
Water pollution effects(Humans) ;
Water pollution effects(Animals) ;
Health hazards ;
Carcinogenicity tests ;
Path of pollutants ;
Mutagenicity tests ;
Enzyme activation
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB90-215435 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
98p |
| Abstract |
Antimony (Sb) is a semimetal element of Group V, sharing some chemical properties with lead, arsenic, and bismuth. The most stable valence states of antimony are Sb(3+) and Sb(5+). Numerous inorganic and organic compounds of antimony are known. Most of the common antimony compounds are slightly to readily soluble in water. Antimony is thought to exert its toxic effects by interacting with intracellular enzymes or cofactors. A number of sulfhydryl-containing compounds reduce the toxic effects of antimony, suggesting that it may bind to cellular sulfhydryl groups. Antimony has been reported to increase the activity of heme oxygenase, to increase the action of thyroid hormone, and to decrease the toxicity of selenium, but the mechanisms of these effects are not known. Antimony has been found to be mutagenic in several test systems, and various types of tumors, including lung neoplasms, have been induced in rats upon inhalation exposure; however, no evidence has been found that orally ingested antimony is carcinogenic. |
| Supplementary Notes |
Sponsored by Environmental Protection Agency, Washington, DC. Office of Drinking Water. |
| NTIS Title Notes |
Draft rept. (Final). |
| Category Codes |
57U; 57Y; 68D |
| NTIS Prices |
PC A05/MF A01 |
| Primary Description |
700/03 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
022219868 |
| Origin |
NTIS |
| Type |
CAT |
