| Main Title |
O-Nitroaniline-Pilot Teratology Study in Rats with Cover Letter. |
| CORP Author |
Monsanto Chemical Co., St. Louis, MO.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1984 |
| Report Number |
878214235 |
| Stock Number |
OTS-0206497 |
| Additional Subjects |
Teratology ;
Toxicity ;
Rats ;
Laboratory animals ;
Toxic substances ;
Hazardous materials ;
Dose levels ;
Pregnancy ;
O-nitroaniline ;
Anilines ;
CAS NO 88-74-4
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0206497 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
40p |
| Abstract |
Groups of 6 mated female Sprague-Dawley derived rats were treated orally with o-nitroaniline (lot no. 1769150) at dosages of 50, 200, 400, 800, and 1200 milligrams/kilogram body weight on days 6 through 15 of gestation. A vehicle (corn oil) control group received corn oil on a comparable regimen. Animals were observed daily for mortality or signs of toxicity. Maternal body weights were recorded at intervals throughout the study. On day 21 of gestation, all surviving females were sacrificed, the number of. corpora lutea were determined, and the uterine horns were examined for implantation sites, resorptions, and the number of viable or nonviable fetuses. The sex and weight of each live fetus was recorded. All fetuses were examined for external malformations. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
13 Apr 1984 |
| Category Codes |
57Y |
| NTIS Prices |
PC A04/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
019000210 |
| Origin |
NTIS |
| Type |
CAT |
