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Main Title Issues That Must Be Addressed When Constructing Anatomical Models of the Developing Lung.
Author Menache, M. G. ; Graham, R. C. ;
CORP Author Northrop Services, Inc., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1988
Report Number EPA-68-02-4450; EPA/600/D-88/023;
Stock Number PB88-170790
Additional Subjects Anatomical models ; Lung ; Air pollution ; Dimensional analysis ; Respiration ; Contaminants ; Toxicity ; Dosimetry ; Air pollution effects(Humans) ; Airway resistance
Library Call Number Additional Info Location Last
NTIS  PB88-170790 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 32p
Abstract Published data on airway dimensions in the developing human lung, including estimated age-dependent changes and experimental data, have been summarized to illustrate the variability and gaps in the data used to develop anatomical models for deposition calculations. A comparison of the morphological dimensions resulting from various assumptions about the volume distribution of pulmonary airways is also presented. Although deposition is not examined here, the varibility in reported measurements underscores the influence that anatomical parameters can have on deposition calculations and the importance of further investigation of lung dimensions to reduce the uncertainties in computer simulations of delivered dose, thereby improving the data base necessary for risk assessment.
Supplementary Notes Sponsored by Health Effects Research Lab., Research Triangle Park, NC.
PUB Date Free Form Feb 88
Category Codes 57A; 57Y; 68A; 68G
NTIS Prices PC A03/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 811327532
Origin NTIS
Type CAT