| Main Title |
Comprehensive progress report for Fourier transform NMR of metals of environmental significance / |
| Author |
Ellis, Paul D.
|
| Other Authors |
|
| CORP Author |
South Carolina Univ., Columbia. Dept. of Chemistry.;Health Effects Research Lab., Research Triangle Park, NC. |
| Publisher |
U.S. Environmental Protection Agency, Health Effects Research Laboratory, |
| Year Published |
1979 |
| Report Number |
EPA 600/1-79/035; EPA-R-804359 |
| Stock Number |
PB80-137490 |
| OCLC Number |
42926089 |
| Subjects |
Nuclear magnetic resonance spectroscopy--Research ;
Metals--Analysis ;
Cadmium--Isotopes--Spectra
|
| Additional Subjects |
Nuclear magnetic resonance ;
Selenium ;
Cadmium ;
Environmental surveys ;
Biochemistry ;
Amino acids ;
Proteins ;
Molecular relaxation ;
Toxicology ;
Public health ;
Probes ;
Pollution ;
Fourier transform spectroscopy ;
Chemical shifts(Nuclear magnetic resonance) ;
Heavy metals ;
Concanavalin A ;
Superoxide dismutase ;
Peptidase/carboxy ;
Cadmium 113 ;
Selenium 77
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EJBD |
EPA 600-1-79-035 |
|
Headquarters Library/Washington,DC |
04/25/2014 |
| EKBD |
EPA-600/1-79-035 |
|
Research Triangle Park Library/RTP, NC |
06/30/2000 |
| ELBD ARCHIVE |
EPA 600-1-79-035 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
| NTIS |
PB80-137490 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
x, 81 pages : figures ; 28 cm. |
| Abstract |
Interactions of the metals cadmium and selenium with various biologically important substrates were studied by nuclear magnetic resonance (NMR) spectroscopy. Cadmium-113 NMR was used for a critical examination of three metalloproteins: concanavalin A, bovine superoxide dismutase and carboxypeptidase A. The NMR parameters of selenium-77 were investigated, with a view to using this nucleus as a probe of active site sulfydryl groups in proteins. Several advances in NMR instrumentation were developed to further the aims of this project. One is a unique NMR probe, capable of spinning large (18 mm) NMR tubes, decoupling at any frequency, and observing any NMR-active nuclei. A decoupler modification, 'Chirp' decoupling, was developed. This modification allows good experimental results with approximately 1/10 the power required without modification. |
| Notes |
"EPA-600/1-79/035." EPA grant no. R804359 ; EPA project officer: Nancy K. Wilson. Includes bibliographical references (pages 53-61). |
| Place Published |
Research Triangle Park, NC |
| Corporate Au Added Ent |
Health Effects Research Laboratory (Research Triangle Park, N.C.); United States. Environmental Protection Agency. Office of Research and Development.; University of South Carolina. Department of Chemistry. |
| Title Ser Add Ent |
Research reporting series. Environmental health effects research ; EPA 600/1-79/035. |
| PUB Date Free Form |
September 1979 |
| Series Title Untraced |
Environmental health effects research series ; EPA 600/1-79/035 |
| NTIS Prices |
PC A05/MF A01 |
| BIB Level |
m |
| Medium |
unmediated |
| Content |
text |
| Carrier |
volume |
| Cataloging Source |
OCLC/T |
| OCLC Time Stamp |
20140418112339 |
| Language |
eng |
| Origin |
OCLC |
| Type |
MERGE |
| OCLC Rec Leader |
02018cam 2200433Ka 45020 |
