||Airway Sensitivity of Asthmatics to Sulfur Dioxide.
Horstman, D. ;
Roger, L. J. ;
Kehrl, H. ;
Hazucha, M. ;
||Health Effects Research Lab., Research Triangle Park, NC. Clinical Research Branch. ;Environmental Monitoring and Services, Inc., Chapel Hill, NC. ;North Carolina Univ. at Chapel Hill.
Sulfur dioxide ;
Respiratory system ;
Air pollution ;
Air pollution effects(Humans) ;
Bronchial provocation tests ;
Sraw(Specific Airway Resistance)
||Some EPA libraries have a fiche copy filed under the call number shown.
||Airways' sensitivity to SO2, (PC(SO2)), was defined as the concentration of SO2 which provoked a 100% increase in specific airways' resistance (SRaw). PC(SO2) was determined for 2. asthmatics performing moderate exercise while exposed to several concentrations of SO2 up to 2.0 ppm. Substantial variability in sensitivity was observed: for 20% of the subjects, PC(SO2) was greater than 1.95 ppm SO2, while for the remaining 80%, it ranged between 0.28 and 1.38 ppm SO2. The median PC(SO2) was 0.75 ppm SO2. PC(SO2) and nonspecific airways' sensitivity to methacholine were not related. (Copyright (c) Toxicology and Industrial Health, Vol. 2, No. 3, 1986.)
||Pub. in Jnl. of Toxicology and Industrial Health, v2 n3 p289-298 1986. Prepared in cooperation with Environmental Monitoring and Services, Inc., Chapel Hill, NC., and North Carolina Univ. at Chapel Hill.
|NTIS Title Notes
||Reprint: Airway Sensitivity of Asthmatics to Sulfur Dioxide.
|PUB Date Free Form
||68G; 57W; 57Y
||PC A02/MF A01