Main Title |
Ozone Response Relationships in Healthy Nonsmokers. |
Author |
Kulle, T. J. ;
Sauder, L. R. ;
Hebel, J. R. ;
Chatham, M. D. ;
|
CORP Author |
Maryland Univ. at Baltimore. Dept. of Medicine.;Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1985 |
Report Number |
EPA/600/J-85/428; |
Stock Number |
PB86-208568 |
Additional Subjects |
Ozone ;
Responses ;
Relationships ;
Reprints ;
Air pollution effects(Humans)
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB86-208568 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
9p |
Abstract |
Significant concentration responses were observed in FVC1 FEV1, FEF 25-75, SGaw, IC, and TLC in 20 healthy, nonsmoking volunteers exposed randomly to 0.00, 0.10, 0.15, 0.20, and 0.25 ppm O3. In addition, significant response changes for FVC1 FEV1, FEF25-75 were shown with time over the 2-h exposure. Intermittent, heavy exercise (VE1 68L/min) lasting 14 min was employed every 30 min during exposure. Inspection of the concentration and time response curves suggests that the threshold for the group response is at or below 0.15 ppm O3. Six subjects experienced decreases > 5% in SGaw at 0.15 ppm. The concentration is only slightly higher than the 1-h O3 National Ambient Air Quality Standard. A dose-related response was also seen for cough, nose and throat irritation, and chest discomfort. The work load, length of exposure, and individual sensitivity must be considered for establishing a safe O3 exposure level. |
Supplementary Notes |
Pub. in American Review of Respiratory Diseases, v132 p36-41 Oct 84. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
NTIS Title Notes |
Journal article. |
Title Annotations |
Reprint: Ozone Response Relationships in Healthy Nonsmokers. |
PUB Date Free Form |
c1985 |
Category Codes |
6T; 57Y; 68A |
NTIS Prices |
PC A02/MF A01 |
Primary Description |
600/11 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
622718399 |
Origin |
NTIS |
Type |
CAT |