| Main Title |
Macrophage Aggregates as Indicators of Environmental Stress. (Chapter 15). |
| Author |
Blazer, V. S. ;
Facey, D. E. ;
Fournie, J. W. ;
Courtney, L. A. ;
Summers, J. K. ;
|
| CORP Author |
Environmental Research Lab., Gulf Breeze, FL. Office of Research and Development. ;National Fish Health Research Lab., Kearneysville, WV. ;Saint Michael's Coll., Colchester, VT. Dept. of Biology. |
| Publisher |
1994 |
| Year Published |
1994 |
| Report Number |
EPA/600/A-94/114; |
| Stock Number |
PB94-190824 |
| Additional Subjects |
Environmental monitoring ;
Water pollution effects(Animals) ;
Biological markers ;
Macrophages ;
Body burden ;
Water quality ;
Sediments ;
Spleen ;
Kidney ;
Liver ;
Aging(Biology) ;
Estuaries ;
Lake Champlain ;
Reprints ;
Lagodon rhomboides ;
Leiostomus xanthurus ;
Bagre marinus
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB94-190824 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
18p |
| Abstract |
The growing awareness of adverse effects of environmental contamination has lead to scrutiny of various biomarkers as early indicators of these effects. The use of splenic macrophage aggregates (MA) as indicators of fish health and environmental degradation was evaluated using three fish species from four sites. The sites were part of the Environmental Protection Agency's Environmental Monitoring and Assessment Program (EMAP). Water quality, benthic and fish community characteristics, sediment and fish tissue contaminant analysis were all conducted at these sites. In addition, tissues from pinfish (Lagodon rhomboides), spot (Leiostomus xanthurus) and gafftopsail catfish (Bagre marinus) were fished in the field. Histological sections of spleen were evaluated using a numerical rating system and image analysis. The MA number, size, and percent of tissue occupied by MAs of each species was compared among sites and related to either tissue or sediment contaminant levels. Spot MA parameters were all significantly higher at the site with the highest sediment contaminant levels. Catfish accumulated high tissue burdens of most contaminants when compared to other fish collected at the same site. Catfish MA parameters were also better indicators of tissue contaminant levels. The usefulness of MA as indicators of environmental stress is supported by this study. Choice of fish species to evaluate sites is discussed. |
| Supplementary Notes |
Pub. in Modulators of Fish Immune Responses: Models for Environmental Toxicology/Biomarkers, Immunostimulators, v1 p169-186 1994. Also pub. as Environmental Research Lab., Gulf Breeze, FL. Office of Research and Development rept. no. CONTRIB-850. Prepared in cooperation with National Fish Health Research Lab., Kearneysville, WV. and Saint Michael's Coll., Colchester, VT. Dept. of Biology. |
| NTIS Title Notes |
Book chapter. |
| Title Annotations |
Reprint: Macrophage Aggregates as Indicators of Environmental Stress. (Chapter 15). |
| Category Codes |
68D; 57Y; 57Z; 57J |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/04 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
424431001 |
| Origin |
NTIS |
| Type |
CAT |
