| Main Title |
Effects of o,p'-DDT on the Adrenal Gland and Hepatic Microsomal Enzyme System in the Beagle Dog. |
| Author |
Copeland, M. F. ;
Cranmer., M. F. ;
|
| CORP Author |
Environmental Protection Agency, Perrine, Fla. Primate and Pesticide Effects Lab. |
| Year Published |
1973 |
| Stock Number |
PB-279 721 |
| Additional Subjects |
Insecticides ;
DDT ;
Pesticides ;
Toxicology ;
Dogs ;
Enzymes ;
Liver ;
Ribosomes ;
Adrenal gland ;
Ingestion(Biology) ;
Laboratory animals ;
Experimental data ;
Physiological effects ;
Tables(Data) ;
Tissues(Biology) ;
Distribution ;
Storage ;
Adrenal cortex ;
Herbicides ;
Reprints ;
Toxic substances ;
DDD insecticide ;
Bioaccumulation
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB-279 721 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
10p |
| Abstract |
Four male beagle dogs received o,p'-DDT (50 mg/kg/day) in corn oil, administered in gelatin capsules, for 32 days. Four dogs used as controls received only corn oil. The treated dogs maintained body weights comparable to the controls and there were no overt signs of toxicity. The treated dogs showed a decreased eosinopenic response to ACTH after day 16. There was no significant difference in the plasma sodium and potassium concentrations or in the hematocrit before or after ACTH, nor in the 17-hydroxycorticosteroid (17-OHCS) response to ACTH between the treated and control dogs on any of the test days. |
| Supplementary Notes |
Pub. in Toxicology and Applied Pharmacology 27, p1-10 1974. |
| Availability Notes |
Included in the report, Journal Articles on Toxicology. Group 9, PB-279 718. |
| Title Annotations |
Reprint: Effects of o,p'-DDT on the Adrenal Gland and Hepatic Microsomal Enzyme System in the Beagle Dog, |
| PUB Date Free Form |
14 May 73 |
| Category Codes |
6T; 57Y; 68G; 68E |
| NTIS Prices |
(Order as PB-279 718, MF A01) |
| Primary Description |
500/01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
323738871 |
| Origin |
NTIS |
| Type |
CAT |
