Main Title |
Survival of Genetically Engineered Microbes in the Environment: Effect of Host/Vector Relationship. |
Author |
Devanas, M. A. ;
Stotzky, G. ;
|
CORP Author |
Rutgers - The State Univ., New Brunswick, NJ. ;New York Univ., NY. Lab. of Microbial Ecology.;Corvallis Environmental Research Lab., OR. |
Year Published |
1988 |
Report Number |
EPA-R-809067 ;EPA-R-812484; EPA/600/D-88/109; |
Stock Number |
PB88-214978 |
Additional Subjects |
Ecology ;
Survival ;
Environment ;
Genetically engineered microbes ;
Environmental fate ;
Biological adaptation ;
Ecosystems
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB88-214978 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
41p |
Abstract |
The fate and survival of genetically engineered microbes is dependent on the survival, establishment, and growth of the microbial host, as well as on the maintenance, replication, and segregation of the recombinant plasmids within the bacterial host population. The interactions of the host and vector with each other and the environment influence the ability of the novel microbe to survive, grow, and possibly transfer its genetic information. Several of these host-vector interactions, i.e., plasmid maintenance, bacterial host fitness, physiological changes in the bacterial host, and gene transfer, have been studied using genetically engineered plasmids. These studies indicate that certain biotic factors, such as competition between the engineered microbe and the indigenous microbiota, generation time, plasmid size and copy number, and abiotic factors, such as clay minerals, nutrients, and moisture, influence the survival of any genetic transfer by engineered microbes in the environment. |
Supplementary Notes |
See also PB88-214960. Prepared in cooperation with New York Univ., NY. Lab. of Microbial Ecology. Sponsored by Corvallis Environmental Research Lab., OR. |
NTIS Title Notes |
Symposium paper. |
PUB Date Free Form |
May 88 |
Category Codes |
57H#; 57K; 57F |
NTIS Prices |
PC A03/MF A01 |
Primary Description |
600/02 |
Document Type |
NT |
Cataloging Source |
NTIS/MT |
Control Number |
821128284 |
Origin |
NTIS |
Type |
CAT |