| Main Title |
Acute Inhalation Toxicity Evaluation in Rats with Zinc Omadine Fps (Final Report) with Cover Letter Dated 01/15/1991. |
| CORP Author |
International Research and Development Corp., Mattawan, MI.; Olin Corp., Baraboo, WI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1991 |
| Report Number |
89-910000145 |
| Stock Number |
OTS0527753-1 |
| Additional Subjects |
Toxicology ;
Health effects ;
Acute Toxicity ;
Mammals ;
Rats ;
Inhalation ;
Toxic substances ;
Laboratory animals ;
CAS No 13463-41-7
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0527753-1 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
91p |
| Abstract |
Zinc omadine (13463-41-7) was evaluated for acute inhalation toxicity in six groups of 5 male and 5 female Sprague-Dawley albino rats exposed to the test material at concentrations of 0.054, 0.14, 0.16, 0.82, 1.4 and 1.5 mg/L for 4 hours. The use of controls was not specified. The animals were observed for 14-days post-exposure. Mortality was observed at all exposure levels, with deaths occurring most frequently on day 1 after exposure. No deaths occurred past day 3 post-exposure. Clinical observations on the day of exposure at all concentration levels included prostration, gasping, labored breathing, rales, trembling and hunched posture. Clinical signs after exposure included urine stained abdomen, labored breathing, rales, lacrimation and red material around the nose/eyes/mouth. Exposure related abnormalities at necropsy were limited to the respiratory tract and were characterized by congestion. Histopathological examination was not specified. The LC50 for males and females combined was 0.14 (0.1-0.2) mg/L. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with Olin Corp., Baraboo, WI. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1991 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A06/MF A06 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028802930 |
| Origin |
NTIS |
| Type |
CAT |
