| Main Title |
Acute Toxicological Properties and Industrial Handling Hazards of Cresol (Ortho, Meta, Para Isomers) Sample Preference. |
| CORP Author |
Dow Chemical Co., Midland, MI.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
11 Jan 1978 |
| Year Published |
1978 |
| Report Number |
878211373; |
| Stock Number |
OTS-0206146 |
| Additional Subjects |
Toxicity ;
Cresols ;
Industrial handling ;
Toxicology ;
Properties ;
Rabbits ;
Skin irritation ;
Eye irritation ;
Lethal doses ;
Meta cresol ;
Ortho cresol ;
Para cresol ;
CAS No 108-39-4 ;
CAS No 95-48-7 ;
CAS No 106-44-5 ;
Acute oral lethality ;
Acute inhalation toxicity
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0206146 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
14p |
| Abstract |
A sample of cresol was submitted to the Comparative Toxicology Research Laboratory for evaluation of acute oral lethality, acute inhalation toxicity, eye irritation properties, skin irritation properties by the method of testing primary irritant substances in accordance with the procedure outlined La the Federal Register, Volume 38, Number 187, Part II, Section 1500.41, and for definition of industrial handling hazards involving acute exposures. A member of the Industrial Health Team (Toxicologist, Industrial Hygienist, and/or Industrial Physician) should be consulted for recommendation of additional safety evaluations or handling procedures which may be needed to support manufacture and/or use of this test material. The acute oral lethality of the test material is low. The acute oral LD50 value determined in 24 albino rats was found to be between 1.0 g/kg and 2.0 g/kg of body weight. The probability that internal injury might result from acute ingestion of amounts of the test material one might encounter incidental to industrial handling is minimal. The test material had an extremely severe effect upon the eyes of an albino rabbit. Direct contact with this material resulted in tissue destruction leading to permanent impairment of vision. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with American Petroleum Inst., Washington, DC. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| Category Codes |
57Y; 68G; 57U; 44G |
| NTIS Prices |
PC A03/MF A01 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
009400480 |
| Origin |
NTIS |
| Type |
CAT |
