| Main Title |
Ames Salmonella/mammalian Microsome Mutagenicity Test and Reverse Mutation Assay - E. Coli Wp2 Uvra a (Standard Plate Test and Preincubation Test) (Oct. 19, 1988) W-letter 12/16/1991. |
| CORP Author |
BASF A.G., Limburgerhof (Germany, F.R.). Agricultural Research Station.; BASF Corp., Mount Olive, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1991 |
| Report Number |
86-920000590 |
| Stock Number |
OTS0535474 |
| Additional Subjects |
Toxicology ;
Health effects ;
4-methylbenzaldehyde (104-87-0) ;
Genotoxicity ;
Gene Mutations ;
Bacteria ;
In Vitro ;
Toxic substances ;
Laboratory animals ;
CAS No 104-87-0
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0535474 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
32p |
| Abstract |
P-Tolualdehyde (CAS No. 104-87-0) was evaluated for mutagenicity in the Ames test (strains TA1535, TA100, TA1537, TA98) with and without metabolic activation (S-9 mix) and in the Escherichia coli (WP2 uvrA) reverse mutation assay at a dose range of 20 ug - 5000 ug/plate in the standard plate test (SPT) and 4 ug - 2500 ug/plate in the preincubation test (PIT). No bacteriotoxic effect was observed with E. coli. Bacteriotoxicity was detected in all Salmonella strains detected at 2500 ug/plate (PIT) and at 5000 ug/plate (SPT). The test substance was determined to be non- mutagenetic. |
| Supplementary Notes |
The quality of the documents listed in the Office of Toxic Substances database may not meet usual NTIS standards but are included to further the opportunity for the scientific and technical community to locate materials which may not be available elsewhere. The content is the responsibility of OTS. Prepared in cooperation with BASF Corp., Mount Olive, NJ. |
| Availability Notes |
Product reproduced from digital image. Order this product from NTIS by: phone at 1-800-553-NTIS (U.S. customers); (703)605-6000 (other countries); fax at (703)605-6900; and email at orders@ntis.gov. NTIS is located at 5285 Port Royal Road, Springfield, VA, 22161, USA. |
| PUB Date Free Form |
1991 |
| Category Codes |
57Y; 57U; 68G; 99; 44G |
| NTIS Prices |
PC A04/MF A04 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
028803390 |
| Origin |
NTIS |
| Type |
CAT |
