| Main Title |
Use of Genetic Activity Profiles in Hazard Evaluation. |
| Author |
Waters, M. D. ;
Stack, H. F. ;
Brady, A. L. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. ;Environmental Health Research and Testing, Inc., Research Triangle Park, NC. |
| Publisher |
Nov 88 |
| Year Published |
1988 |
| Report Number |
EPA/600/D-88/246; |
| Stock Number |
PB89-129415 |
| Additional Subjects |
Profiles ;
Hazardous materials ;
Mutagenicity tests ;
Toxicity ;
Carcinogens ;
Mutagens ;
Laboratory animals ;
Concentration(Composition) ;
Health effects ;
Dibromochloropropane ;
Risk assessment ;
Propane/dibromo-chloro
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB89-129415 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
23p |
| Abstract |
A methodology has been developed to display and evaluate multiple test quantitative information on genetic toxicants for purposes of hazard/risk assessment. Dose information is collected from the open literature: either the lowest effective dose or the highest ineffective dose tested is recorded for each agent and bioassay system. For each agent in the data base, the quantitative results from genetic and related test systems are represented by computer-generated bar graphs 'genetic activity profiles.' Bioassay systems are organized according to classes of genetic activity and subdivided by the phylogenetic level of the test organism. Genetic activity profiles were prepared 187 chemicals, e.g., dibromochloropropane, for the use of the International Agency for Research on Cancer (IARC) Working Group. |
| Supplementary Notes |
Prepared in cooperation with Environmental Health Research and Testing, Inc., Research Triangle Park, NC. |
| Category Codes |
57Y; 57F; 68G; 44G |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
902621854 |
| Origin |
NTIS |
| Type |
CAT |
