| Main Title |
Survival Curves and Incidence of Neoplastic and Non-Neoplastic Disease in SENCAR Mice. |
| Author |
Conti, C. J. ;
Clapp, N. ;
Klein-Szanto, A. J. P. ;
Nesnow, S. ;
Slaga, T. J. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. ;Texas Univ. System Cancer Center, Houston. ;Oak Ridge Associated Universities, Inc., TN. |
| Year Published |
1985 |
| Report Number |
EPA/600/J-85/268; |
| Stock Number |
PB86-160025 |
| Additional Subjects |
Neoplasms ;
Diseases ;
Laboratory animals ;
Incidence ;
Survival ;
Mice ;
Reprints ;
Carcinogenesis
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB86-160025 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
6p |
| Abstract |
The survival curves and the incidence of spontaneous diseases were studied in a population of SENCAR mice, a stock derived by a selected breeding protocol for enhanced susceptibility to chemical carcinogenesis in the skin. SENCAR mice proved to be as long-lived as other mouse strains or stocks, including one of their parental lines, Charles River CD-1. The most frequently occurring neoplasias in SENCAR mice were lymphoma, myeloid leukemia and reticulum cell sarcoma. Other frequently occurring neoplastic diseases included lung adenomas and carcinoma and mammary gland carcinoma. However, the incidence of these tumors was not higher than the incidence in CD-1 mice or other mouse strains or stocks. |
| Supplementary Notes |
Prepared in cooperation with Texas Univ. System Cancer Center, Houston, and Oak Ridge Associated Universities, Inc., TN. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Survival Curves and Incidence of Neoplastic and Non-Neoplastic Disease in SENCAR Mice. |
| PUB Date Free Form |
c1985 |
| Category Codes |
6E; 57E |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
612914908 |
| Origin |
NTIS |
| Type |
CAT |
