| Main Title |
Genes for Tumor Markers are Clustered with Cellular Proto-Oncogenes on Human Chromosomes. |
| Author |
Hozier, J. C. ;
Mass, M. J. ;
Siegfried, J. M. ;
|
| CORP Author |
Florida Inst. of Tech., Melbourne. ;Environmental Health Research and Testing, Inc., Research Triangle Park, NC.;Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1987 |
| Report Number |
EPA-R-8117730-11; EPA/600/J-87/255; |
| Stock Number |
PB88-182373 |
| Additional Subjects |
Malignant neoplasms ;
Genes ;
Mapping ;
Peptides ;
Cells(Biology) ;
Markers ;
Abnormalities ;
Hypothesis ;
Tests ;
Analysis ;
Chromosomes ;
Reprints ;
Oncogenes ;
Karyotyping
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB88-182373 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
13p |
| Abstract |
The relative mapping positions of genes for polypeptides expressed abnormally in tumors (tumor markers) and cellular proto-oncogenes were analyzed and a remarkable degree of co-mapping of tumor marker genes with oncogenes in the human karyotype were found. It is proposed that aberrant expression of marker genes in tumors may be related to their proximity in the human genome to oncogenes expressed during the development of malignancy. Ways to test this hypothesis of concerted abnormal gene expression in mammalian tumor cells are suggested. (Copyright (c) 1987 Elsevier Scientific Publishers Ireland Ltd.) |
| Supplementary Notes |
Pub. in Cancer Letters 36, p235-245 Sep 1987. Prepared in cooperation with Environmental Health Research and Testing, Inc., Research Triangle Park, NC. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Genes for Tumor Markers are Clustered with Cellular Proto-Oncogenes on Human Chromosomes. |
| PUB Date Free Form |
c1987 |
| Category Codes |
57F; 57B; 57D |
| NTIS Prices |
PC A03/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
816221994 |
| Origin |
NTIS |
| Type |
CAT |
