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OLS Field Name OLS Field Data
Main Title EPA Priorities for Biologic Markers Research in Environmental Health.
Author Fowle, J. R. ; Sexton, K. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Publisher c1992
Year Published 1992
Report Number EPA/600/J-93/123;
Stock Number PB93-181113
Additional Subjects Biological markers ; Environmental health ; Exposure ; Epidemiology ; Risk assessment ; Toxicity ; Pollution effects(Humans) ; Public health ; Reprints ; Biomarkers
Library Call Number Additional Info Location Last
NTIS  PB93-181113 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 08/23/1993
Collation 9p
Abstract Recent advances in molecular and cellular biology allow for measurement of biologic events or substances that may provide markers of exposure, effect or susceptibility in humans. The application of these new and emerging techniques to environmental health offers the possibility of significantly reducing the uncertainties that traditionally hamper risk assessments. The EPA health research program places a high priority on the validation of appropriate biologic markers and their application to high priority Agency issues. The rationale for EPA's biomarker research program is presented and future research directions are discussed. Exposure biomarkers will receive most of the research emphasis in the near term, particularly body burden indicators of exposures to high priority chemicals, such as benzene, ozone, selected heavy metals, and organophosphate pesticides. Research on effects biomarkers will attempt to validate the relationship between the observed biological effects and adverse health consequences in humans, especially for cancer, pulmonary toxicity, neurotoxicity, and reproductive/developmental toxicity.
Supplementary Notes Pub. in Environmental Health Perspectives, v98 p235-241 Nov 92. See also PB91-211912 and PB93-116168.
NTIS Title Notes Journal article.
Title Annotations Reprint: EPA Priorities for Biologic Markers Research in Environmental Health.
Category Codes 68G; 57B; 57Y; 57U
NTIS Prices PC A02/MF A01
Primary Description 600/10
Document Type NT
Cataloging Source NTIS/MT
Control Number 316134250
Origin NTIS
Type CAT