| Main Title |
Toxicity of Guthion (Trade Name) and Guthion (Trade Name) 2S to 'Xenopus laevis' Embryos. |
| Author |
Schuytema, G. S. ;
Nebeker, A. V. ;
Griffis, W. L. ;
|
| CORP Author |
Corvallis Environmental Research Lab., OR. |
| Publisher |
c1994 |
| Year Published |
1994 |
| Report Number |
EPA/600/J-94/367; |
| Stock Number |
PB94-209731 |
| Additional Subjects |
Toxicity ;
Water pollution effects(Animals) ;
Frogs ;
Pesticides ;
Amphibia ;
Embryos ;
Teratogens ;
Assaying ;
Dose-response relationships ;
Mortality ;
Abnormalities ;
Lethal dosage ;
Reprints ;
Guthion(Trademark) ;
Xenopus laevis ;
FETAX(Frog Embryo Teratogenesis Assay-Xenopus)
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB94-209731 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
6p |
| Abstract |
Differences in sensitivity to waterborne contaminants between wildlife species have prompted investigations on the sensitivity of amphibiams to potentially hazardous environmental chemicals. The development of Xenopus laevis (African clawed frog) embryos exposed to the pesticide Guthion(Trademark) (technical grade) and Guthion(Trademark) 2S (commercial formulation) was evaluated in modified Frog Embryo Teratogenesis Assay--Xenopus (FETAX) tests. The embryos were exposed to five or six increasing concentrations of pesticide in 10- and 100-ml exposure volumes of test solution for 96 h. Embryos exposed to 10-ml volumes of Guthion exhibited increased mortality, increased deformation, and decreased size as compared to those exposed in 100-ml volumes. LC50s for embryos exposed in the 10-ml Guthion tests ranged from 6.1 to 6.3 mg/L as compared to 10.6 to 11.9 mg/L for those in the 100-ml tests. |
| Supplementary Notes |
Pub. in Archives of Environmental Contamination and Toxicology 27, p250-255 1994. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Toxicity of Guthion (Trade Name) and Guthion (Trade Name) 2S to 'Xenopus laevis' Embryos. |
| Category Codes |
57Y; 68E |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/02 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
428724348 |
| Origin |
NTIS |
| Type |
CAT |
