| Main Title |
Synthesis of New Cyclopenta-Fused PAH (Polycyclic Aromatic Hydrocarbons) Isomers of Cata-Annelated Benzenoid Systems (Journal Version). |
| Author |
Sangaiah, R. ;
Gold, A. ;
|
| CORP Author |
North Carolina Univ. at Chapel Hill. School of Public Health.;Health Effects Research Lab., Research Triangle Park, NC. |
| Publisher |
c1987 |
| Year Published |
1987 |
| Report Number |
EPA-R-811817; EPA/600/J-87/387; |
| Stock Number |
PB89-101125 |
| Additional Subjects |
Aromatic polycyclic hydrocarbons ;
Chemical reactions ;
Reprints ;
Benzaceanthrylene ;
Benzacephenanthrylene ;
CAS 19770-52-6 ;
CAS 16683-64-0 ;
CAS 216-48-8
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB89-101125 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
8p |
| Abstract |
The syntheses of three new benz-annelated derivatives of aceanthrylene and acephenanthrylene are reported. These systems are of interest in studies on mechanisms of bioactivation and structure-activity correlations because of their predicted high level of biological activity. Of the three isomers, benz(d)aceanthrylene has been synthesized by two routes involving Friedel-Crafts acylations of 1,2,3,4-tetrahydronaphthacene with chloroacetyl chloride or oxalyl chloride as the key step. The cyclic ketone product from each route has been successfully elaborated. Synthesis of benz(k)aceanthrylene involves preparation of acenaphthene-3,4-di-carboxylic anthdride and its smooth conversion. A straightforward and high-yield synthesis of benz(j)acephenanthrylene is described utilizing a Robinson annelation reaction of methyl vinyl ketone with a previously reported ketonic precursor of acephenanthrylene. (Copyright (c) 1987 American Chemical Society.) |
| Supplementary Notes |
Pub. in Jnl. of Organic Chemistry, v52 p3205-3211 1987. Sponsored by Health Effects Research Lab., Research Triangle Park, NC. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Synthesis of New Cyclopenta-Fused PAH (Polycyclic Aromatic Hydrocarbons) Isomers of Cata-Annelated Benzenoid Systems (Journal Version). |
| Category Codes |
99D |
| NTIS Prices |
Not available NTIS |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
834420754 |
| Origin |
NTIS |
| Type |
CAT |
