| Main Title |
Synthesis of 3-(14)C-3-Chlopo-4-(Dichloromethyl)-5-Hydroxy-2(5H)-Furanone and Its Use in a Tissue Distribution Study in the Rat. |
| Author |
Ringhand, H. P. ;
Kaylor, W. H. ;
Miller, R. G. ;
Kopfler, F. C. ;
|
| CORP Author |
Health Effects Research Lab., Cincinnati, OH. Toxicology and Microbiology Div. |
| Publisher |
c1989 |
| Year Published |
1989 |
| Report Number |
EPA/600/J-89/065; |
| Stock Number |
PB90-103714 |
| Additional Subjects |
Chemical reactions ;
Furans ;
Bromine ;
Rats ;
Carbon dioxide ;
Urine ;
Feces ;
Dosage ;
Blood chemical analysis ;
Reprints ;
Pharmacokinetics ;
3-(14)C-3-chloro-4(dichloromethyl)-5-hydroxy-2(5H)-furanone ;
Bromoacetic-2-(14)C acid ;
Tissue distribution ;
Carbon radioisotopes ;
Volatile organic compounds
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB90-103714 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
10p |
| Abstract |
A procedure for the synthesis of (14)C-MX using bromoacetic-2-(14)C acid as the starting material was developed. Use of the radiolabeled product in a distribution study in the rat indicated that the majority of the radioactivity was cleared in feces (47%) and urine (33%) within 48 hours. The parent compound was not detected in blood samples taken after 48 hours or in the feces and urine samples. |
| Supplementary Notes |
Pub. in Chemosphere, v18 n11-12 p2229-2236 Jun 89. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Synthesis of 3-(14)C-3-Chlopo-4-(Dichloromethyl)-5-Hydroxy-2(5H)-Furanone and Its Use in a Tissue Distribution Study in the Rat. |
| Category Codes |
99D; 57Y; 57D; 68G |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
932617134 |
| Origin |
NTIS |
| Type |
CAT |
