| Main Title |
Neonatal Triethyltin Exposure Alters Adult Electrophysiology in Rats. |
| Author |
Dyer, Robert S. ;
Howell, William E. ;
Reiter, Lawrence W. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1981 |
| Report Number |
EPA-600/J-81-163; |
| Stock Number |
PB83-189589 |
| Additional Subjects |
Toxicology ;
Physiological effects ;
Rats ;
Laboratory animals ;
Reprints ;
Triethyltin
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB83-189589 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
17p |
| Abstract |
In adults, triethyltin (TET) produces degeneration of white mater, edema, vacuolization of myelin and histoxic hypoxia. To determine the functional consequences of perinatal exposure to TET, albino rats were administered either 0,3,6, or 9 mg/kg TET on postnatal day 5. Upon reaching adulthood, the rats were implanted with electrodes for recording visual evoked potentials (VEPs) and hippocampal afterdischarges (ADs). In addition to these tests, 17 days of kindling trials were administered to the rats followed by testing with pentylenetetrazol and picrotoxin for seizure susceptibility. |
| Supplementary Notes |
Pub. in Neurotoxicology 2, p609-623 1981. |
| NTIS Title Notes |
Journal article. |
| Title Annotations |
Reprint: Neonatal Triethyltin Exposure Alters Adult Electrophysiology in Rats. |
| PUB Date Free Form |
5 May 81 |
| Category Codes |
6T; 57Y |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
320323404 |
| Origin |
NTIS |
| Type |
CAT |
