| Main Title |
Dominant Lethal Effects of Subchronic Acrylamide Administration in the Male Long-Evans Rat. |
| Author |
Smith, M. K. ;
Zenick, H. ;
Preston, R. J. ;
George, E. L. ;
Long, R. E. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. ;Cincinnati Univ., OH. Dept. of Environmental Health. ;Oak Ridge National Lab., TN. |
| Year Published |
1986 |
| Report Number |
EPA/600/J-86/059; |
| Stock Number |
PB86-204633 |
| Additional Subjects |
Toxicology ;
Bioassay ;
Vinyl ;
Dosage ;
Acrylamide ;
Neurotoxicity
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB86-204633 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
7p |
| Abstract |
Acrylamide, a widely used vinyl monomer, is well known as a neurotoxin but inactive as a mutagen in bacterial test systems. The experiments reported demonstrate that after subchronic oral dosing in the male rat, acrylamide induced significant elevations in both pre and post implantation loss following dominant lethal testing. These effects were seen at doses which failed to produce clinical or pathological evidence of neurotoxicity. |
| Supplementary Notes |
Pub. in Mutation Research 173, p273-277 Mar 86. Prepared in cooperation with Cincinnati Univ., OH. Dept. of Environmental Health, and Oak Ridge National Lab., TN. |
| NTIS Title Notes |
Journal article. |
| PUB Date Free Form |
c1986 |
| Category Codes |
6T; 57Y |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
621324574 |
| Origin |
NTIS |
| Type |
CAT |
