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Main Title Quantitative Assessment of Cancer Risk from Exposure to Diesel Engine Emissions.
Author Pepelko, W. E. ; Chen, C. ;
CORP Author Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher c1993
Year Published 1993
Report Number EPA/600/J-93/188 ;OHEA-C-502;
Stock Number PB93-222081
Additional Subjects Pulmonary neoplasms ; Diesel engine exhaust ; Risk ; Bioassay ; Tests ; Rats ; Dosimetry ; Epithelium ; Coal tar ; Respiration ; Reprints ;
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NTIS  PB93-222081 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 16p
Abstract Quantitative estimates of lung cancer risk from exposure to diesel engine emissions were developed using data from three chronic bioassays with Fischer 344 rats. Human target organ dose was estimated with the aid of a comprehensive dosimetry model. The epithelial tissue lining the alveoli and lower airways is the primary target site for induction of lung tumors. Dose was therefore based upon the concentration of carbon particulate matter per unit lung surface area.
Supplementary Notes Pub. in Regulatory Toxicology and Pharmacology 17, p52-65, 1993.
NTIS Title Notes Journal article.
Title Annotations Reprint: Quantitative Assessment of Cancer Risk from Exposure to Diesel Engine Emissions.
Category Codes 68G; 68A; 97R
NTIS Prices PC A03/MF A01
Primary Description 600/21
Document Type NT
Cataloging Source NTIS/MT
Control Number 328019503
Origin NTIS
Type CAT