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OLS Field Name OLS Field Data
Main Title Dose Response of Elastase-Induced Emphysema in Hamsters.
Author Raub, James A. ; Mercer, Robert R. ; Miller, Frederick J. ; Graham, Judith A. ; O'Neil, John J. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1981
Report Number EPA-600/J-81-332;
Stock Number PB82-248048
Additional Subjects Emphysema ; Respiratory diseases ; Toxicology ; Hamsters ; Laboratory animals ; Air pollution ; Reprints ; Pancreatopeptidase ; Air pollution effects(Animals) ; Lung function tests
Holdings
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NTIS  PB82-248048 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/23/1988
Collation 6p
Abstract Elastase-induced emhysema in hamsters was studied using pulmonary function tests in an effort to develop techniques for determining the effects of air pollutants on the progression of this disease. It appears that as little as 6 units of elastase produces mild emphysema in hamsters, which is detectable by pulmonary function testing. Of the tests, the DLCO and N2 slope were the most effective in detecting the degree of impairment.
Supplementary Notes Pub. in American Review of Respiratory Diseases 125, p432-435 1982.
NTIS Title Notes Journal article.
Title Annotations Reprint: Dose Response of Elastase-Induced Emphysema in Hamsters.
PUB Date Free Form 26 Oct 81
Category Codes 6T; 6F; 57Y; 68A
NTIS Prices PC A02/MF A01
Primary Description 600/11
Document Type NT
Cataloging Source NTIS/MT
Control Number 323822057
Origin NTIS
Type CAT