| Main Title |
Biochemical, Functional and Morphological Indicators of Neurotoxicity: Effects of Acute Administration of Trimethyltin to the Developing Rat. |
| Author |
Miller, D. B. ;
O'Callaghan, J. P. ;
|
| CORP Author |
Health Effects Research Lab., Research Triangle Park, NC. |
| Year Published |
1984 |
| Report Number |
EPA/600/J-84/262; |
| Stock Number |
PB85-193845 |
| Additional Subjects |
Organometallic compounds ;
Toxicity ;
Morphology ;
Bioassay ;
Rats ;
Brain ;
Hippocampus ;
Behavior ;
Learning ;
Trimethyltin compounds ;
Neutrotoxins ;
Dose rate
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
PB85-193845 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
10p |
| Abstract |
The neurotoxic organometal, trimethyltin (TMT), was administered to rats on postnatal day (PND)5. Neurotoxicity was assessed throughout subsequent development using morphological, biochemical and functional endpoints. These consisted of brain weight measures and histology (morphology), assays of nervous system-specific proteins (biochemistry) and neurobehavioral indices of activity and learning (function). All three indices were affected. |
| Supplementary Notes |
Pub. in Jnl. of Pharmacology and Experimental Therapeutics 231, n3 p744-751 Dec 84. |
| NTIS Title Notes |
Journal article. |
| PUB Date Free Form |
1984 |
| Category Codes |
6T; 57Y |
| NTIS Prices |
PC A02/MF A01 |
| Primary Description |
600/11 |
| Document Type |
NT |
| Cataloging Source |
NTIS/MT |
| Control Number |
519922077 |
| Origin |
NTIS |
| Type |
CAT |
